Turkish Adaptation of the VascuQoL-6 Quality of Life Scale

Uşak University

Status: Invitation-only

Conditions: Quality of Life; Behcet Disease; Takayasu Arteritis

Study type: Observational

Funder types: Other

Identifiers

NCT06979245

E-60116787-020-494225

Details and patient eligibility

About

Study type: Observational study Primary objective: The aim of this study was to examine the validity and reliability of the Vascular Quality of Life Questionnaire-6 (VascuQoL-6) in Turkish in individuals diagnosed with Takayasu Arteritis or Vascular Behçet's disease.

The main questions it aims to answer are:

Can VascuQoL-6 measure disease-related quality of life validly and reliably? Does the scale show significant correlations with measures such as SF-36, EQ-5D-3L, BDCAF, BSAS and ITAS-2010? There is no comparison group.

Participants will be asked to:

Contribute to the translation process of the scale into Turkish, Complete all quality of life forms in the first assessment, Participate in the test-retest analysis by re-filling VascuQoL-6 one week later.

Full description

Takayasu arteritis (TA) is a rare, systemic granulomatous large vessel vasculitis that primarily affects the aorta and its branches. Although all major arteries can be affected, the descending and ascending aorta, subclavian arteries, and carotid arteries are most commonly affected. Inflammation can lead to intimal proliferation and stenosis or destruction of the vascular structure and aneurysmal degeneration. TA is a disease with profound consequences on quality of life.

Behçet's disease is a multisystemic, chronic inflammatory vasculitis characterized by skin and mucosal lesions.

The vascular involvement of Behçet's disease has characteristic features. The most important difference between Behçet's disease and other vasculitides is that venous involvement is more prevalent than arterial involvement. Many different symptoms can coexist with vascular involvement, and these symptoms require different treatments. BD characterized by vascular involvement may be a cluster different from the typical clinical setting and may differ from the typical symptomatic group in terms of treatment resistance and prognosis.

It is recommended that objective outcome measures be complemented by patient-reported outcome measures. Such measures, when integrated into daily clinical practice, are useful in clinical decision making and can also provide important information about the results of different interventions. Therefore, it is widely recommended to use disease-specific health-related quality of life instruments. Because outcome measures that focus on the specific limitations experienced by patients are made sensitive to detecting significant changes in health status in response to treatment. The Vascular Quality of Life (VascuQoL) questionnaire was developed by Morgan et al in 2001 and has been translated into 7 languages.

The aim of this study was to examine the validity and reliability of the Turkish version of the Vascular Quality of Life Questionnaire-6 in patients diagnosed with Takayasu Arteritis and Vascular Behçet's disease.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Being between the ages of 18-65
• Being willing to participate in the study
• Being diagnosed with Takayasu Arteritis or Vascular Behçet's disease by a rheumatologist

Exclusion criteria

• Having another disease that will affect their physical condition
• Having a cognitive disability that will prevent them from cooperating
• Being pregnant
• Having a neurological disease (hemiplegia, Parkinson's, multiple sclerosis, vertigo, epilepsy, etc.)
• Having undergone any surgery in the last year
• Having another simultaneous rheumatic disease

Trial design

30 participants in 1 patient group

Those diagnosed with Takayasu Arteritis or Vascular Behçet's disease

Description:

The study group was diagnosed with Takayasu Arteritis or Vascular Behçet's disease by a rheumatologist.