Turkish Version of the Parent-Reported Drug Hypersensitivity Quality of Life Questionnaire

Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization

Status: Completed

Conditions: Quality of Life (QOL); Allergy and Immunology; Drug Hypersensitivity; Caregivers

Treatments: Behavioral: Turkish Version of the P-DrHy-Q

Study type: Observational

Funder types: Other

Identifiers

NCT07069439

2025-300613

Details and patient eligibility

About

This study aims to evaluate the psychometric properties of the Turkish version of the Parent-reported Drug Hypersensitivity Quality of Life Questionnaire (P-DrHy-Q), a disease-specific instrument assessing the health-related quality of life (HRQoL) in caregivers of children with suspected or confirmed drug hypersensitivity reactions. The P-DrHy-Q is designed to capture the psychosocial burden experienced by caregivers and includes two main domains: Mental Health and Social Activity. This study involves a forward-backward translation process, cultural adaptation, internal consistency analysis, and test-retest reliability assessment in a Turkish caregiver population.

Enrollment: 74 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years
• Primary caregiver of a child under the age of 18
• Child must have a documented history of drug hypersensitivity
• Fluent in written and spoken Turkish
• Willingness to participate and provide written informed consent
• Availability to complete both baseline and follow-up questionnaire within the designated time frame

Exclusion criteria

• Caregivers with diagnosed psychiatric or cognitive disorders
• Inability to read or write in Turkish
• Child currently experiencing an acute drug hypersensitivity reaction
• Previous participation in the pilot testing phase of this validation study

Trial design

74 participants in 1 patient group

Caregiver Cohort

Description:

This cohort will consist of adult caregivers (parents or legal guardians) of children under 18 years of age with a documented history of drug hypersensitivity. Participants will complete the Turkish version of the Parent-reported Drug Hypersensitivity Quality of Life Questionnaire (P-DrHy-Q) to evaluate its psychometric properties, including internal consistency and test-retest reliability.

Treatment:

Behavioral: Turkish Version of the P-DrHy-Q