Turmeric for Patients With Basal Joint Arthritis

Mass General Brigham

Status: Enrolling

Conditions: Thumb Osteoarthritis

Treatments: Other: Placebo; Dietary Supplement: Turmeric

Study type: Interventional

Funder types: Other

Identifiers

NCT03017118

2016P001402

Details and patient eligibility

About

The aim of this study is to assess whether the use of a commercially available nutraceutical, turmeric, is an effective option to manage pain and stiffness in patients with basal joint arthritis. To conduct a pilot Randomized Controlled Trial evaluating the impact of turmeric on basal joint arthritis.

Enrollment: 20 estimated patients

Sex: All

Ages: 40+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 40 years of age or older
• English fluency and literacy
• Seeking care for basal joint pain
• Tender over basal joint
• Positive distraction rotation test (rotation of the thumb metacarpal base while applying axial traction)
• Radiographic evidence of Eaton stage 1 and 2 only

Exclusion criteria

• Secondary gains (litigations or worker compensation) procedures that may interfere with patients' motivation for treatment
• Inability or unwillingness to participate in a trial study
• Rheumatoid Arthritis or other inflammatory disorder diagnoses
• Post-traumatic osteoarthritis
• Patients on Coumadin/Steroids/NSAIDs/Tylenol
• Diabetes Mellitus
• Pregnant or lactating women
• Basal joint arthritis of Eaton stage 3
• Patients seeking other treatment for their basal joint arthritis (splint, corticosteroid injection, surgery)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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20 participants in 2 patient groups, including a placebo group

Turmeric

Experimental group

Description:

Subjects in this group will receive turmeric (100 mg pastille) 3 times per day for 6 weeks.

Treatment:

Dietary Supplement: Turmeric

Control

Placebo Comparator group

Description:

Subjects in this group will receive a placebo pill 3 times per day for 6 weeks.

Treatment:

Other: Placebo