TWIST Human Gene and Cleft Lips and Palates

University Hospital, Strasbourg, France

Status: Terminated

Conditions: Cleft Lip

Treatments: Other: None: molecular genetics diagnosis procedure only

Study type: Interventional

Funder types: Other

Identifiers

NCT00213889

2602

Details and patient eligibility

About

This study uses a sequence analysis for TWIST and other craniofacial development genes, among patients presenting with facial clefting.

Enrollment: 45 patients

Sex: All

Ages: 1+ month old

Volunteers: No Healthy Volunteers

Inclusion criteria

Patients aged from 1 month to 18 years:

• Parents agree to enrollment or patients, themselves, agree to enrollment when able to do so
• Healthcare insurance holders
• Display facial clefting

Grown patients over 18 years of age:

• Agree to enrollment
• Display facial clefting
• Healthcare insurance holders

Exclusion criteria

• Patients declining enrollment
• Patients without healthcare insurance

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)