Two- and Three-Dimensional Quantification of Facial Symmetry After Fat Grafting and Free Flap Reconstruction in Hemifacial Atrophy

Peking Union Medical College

Status: Completed

Conditions: Hemifacial Atrophy

Study type: Observational

Funder types: Other

Identifiers

NCT07305909

2024-344 (Other Identifier)

Details and patient eligibility

About

Hemifacial atrophy causes one side of the face to become smaller, leading to facial asymmetry. Surgeons often restore facial volume using either autologous fat grafting or free-flap reconstruction. However, it is not fully clear how much facial symmetry improves after surgery when measured objectively using two-dimensional (2D) photographs and three-dimensional (3D) surface scans.

This is a single-center, retrospective observational study of patients with hemifacial atrophy treated between January 2020 and December 2023 at [Plastic Surgery Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College]. We will quantify facial symmetry before surgery and at the first follow-up visit occurring at or beyond 6 months after the initial surgery. Symmetry outcomes will be assessed using standardized 2D photographs for all included patients, and 3D surface scans for a subset of patients. Complications will also be assessed at the first ≥6-month follow-up visit. We will compare changes in symmetry between patients treated with fat grafting and those treated with free-flap reconstruction.

Enrollment: 60 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

Diagnosis of hemifacial atrophy (Parry-Romberg syndrome).

Underwent initial soft-tissue augmentation with either autologous fat grafting or free-flap reconstruction at the study center between January 2020 and December 2023.

Availability of standardized preoperative assessment and postoperative assessment at the first follow-up visit occurring ≥6 months after surgery (2D photographs required).

Exclusion criteria

Follow-up <6 months after the initial surgery.

Missing key imaging/photographic data required for outcome assessment.

Any additional facial augmentation or revision procedure performed before the first ≥6-month follow-up visit.

Trial design

60 participants in 2 patient groups

Fat Grafting

Description:

Patients with hemifacial atrophy who underwent autologous fat grafting as the initial soft-tissue augmentation procedure. Outcomes were assessed preoperatively and at the first follow-up visit occurring ≥6 months postoperatively.

Free Flap Reconstruction (ALT)

Description:

Patients with hemifacial atrophy who underwent anterolateral thigh (ALT) free-flap reconstruction as the initial soft-tissue augmentation procedure. Outcomes were assessed preoperatively and at the first follow-up visit occurring ≥6 months postoperatively.