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Two Types of PRF Membranes in Management of Dehiscence Defect in Posterior Mandible

A

Alexandria University

Status

Completed

Conditions

Atrophic Mandible

Treatments

Other: e-PRF membrane will be used with xenograft simultaneously with implant placement.
Other: PRF membrane will be used with xenograft simultaneously with implant placement

Study type

Interventional

Funder types

Other

Identifiers

NCT07164417
0936-06/2024

Details and patient eligibility

About

Background: Placement of implants in an atrophic posterior ridge is a challenge for so many clinicians. The success of dental implants depends on the volume of alveolar bone available to provide stability. Bone grafting using xenograft with PRF and e-PRF as a membrane has shown promising results in both bone healing and defect reconstruction. Aim of the study: to evaluate the effect of Platelet-rich fibrin (PRF) and Extended Platelet-rich fibrin (e-PRF) as a membrane with xenograft to increase the width of ridge in posterior mandible with simultaneous implant placement.

Enrollment

20 patients

Sex

All

Ages

20 to 50 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patient with one or more missing posterior mandibular teeth.
  • Patient with atrophic posterior mandible with residual ridge width in the range of 4 to 6mm.
  • Patient with good oral hygiene and acceptable inter-arch space less than or equal to the restoration

Exclusion criteria

  • The patient underwent alveolar ridge reconstruction in the same area.
  • Patients with immune diseases, uncontrolled hypertension, and uncontrolled diabetes.
  • Patient with any pathological condition at the site of surgery.
  • Heavy smoker, alcohol abuse, parafunctional habits.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

20 participants in 2 patient groups

PRF
Active Comparator group
Treatment:
Other: PRF membrane will be used with xenograft simultaneously with implant placement
e-PRF
Experimental group
Treatment:
Other: e-PRF membrane will be used with xenograft simultaneously with implant placement.

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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