Type 1 Diabetes Mellitus Effect on Bone Mineral Density

Creighton University

Status: Completed

Conditions: Osteoporosis; Diabetes Mellitus

Study type: Observational

Funder types: Other

Identifiers

NCT01633684

Creighton 14

Details and patient eligibility

About

Because the diabetics are fracturing at a younger age than the general population (12), this leads us to believe there are significant factors that lead to fracture in Type 1 diabetes mellitus (DM) other than bone mineral density (BMD). Very little longitudinal data exists on BMD in adults with Type 1 DM and the effects of glucose control on BMD. No longitudinal data exists on pQCT in adults with Type 1 DM.

Hypothesis: Adult subjects with diabetes and poor glucose control will lose bone mineral density (BMD) as measured by DXA compared to age and sex matched healthy controls.

Full description

Because the diabetics are fracturing at a younger age than the general population(12), this leads us to believe there are significant factors that lead to fracture in Type 1 DM other than BMD. Very little longitudinal data exists on BMD in adults with Type 1 DM and the effects of glucose control on BMD. No longitudinal data exists on pQCT in adults with Type 1 DM.

Hypothesis: Adult subjects with diabetes and poor glucose control will lose bone mineral density (BMD) as measured by DXA compared to age and sex matched healthy controls.

Enrollment: 123 patients

Sex: All

Ages: 19 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• diabetic patients must have completed Visit 1 of the previous study.

Trial design

123 participants in 2 patient groups

Diabetes

Description:

patients with Type 1 Diabetes Mellitus

Control

Description:

Age and sex matched control subjects