Tyrosine Allergoid Paediatric and Adult Study

Allergy Therapeutics

Status: Active, not recruiting

Conditions: Allergic Conjunctivitis; Allergic Asthma; Allergic Rhinitis Due to Pollen

Treatments: Drug: MATA trees or MATA grass

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT05186025

TAPAS

Details and patient eligibility

About

The primary objective of this 5-year study is to demonstrate non-inferiority of children compared to adults by exploring long-term effectiveness after treatment with TA Bäume (trees) and TA Gräser (grass) following a perennial posology.

Enrollment: 320 patients

Sex: All

Ages: 5+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients from 5 years of age who are treated with TA Gräser top or TA Bäume top due to rhinitis, conjunctivitis and/or mild to moderate bronchial asthma, which are caused by an IgE-mediated allergy to grass and rye pollen or birch, alder and hazel pollen according to the respective SmPC.
• Patients will only be included in this study after the decision on the treatment has been made.

Exclusion criteria

• History of allergen-specific immunotherapy (SIT) for trees or grass within the last 5 years
• If it´s intended to treat the patient with only a preseasonal therapy
• A patient should also not be included in the presence of any of the conditions listed in the respective SmPC

Trial design

320 participants in 2 patient groups

Adults

Description:

adult patients aged ≥ 18 with rhinitis, conjunctivitis and/or mild to moderate bronchial asthma, caused by an IgE-mediated allergy to grass/rye or tree pollen; who are treated with MATA grass or MATA trees as part of their routine medical care

Treatment:

Drug: MATA trees or MATA grass

Children

Description:

children aged from \>5 to 17 years with rhinitis, conjunctivitis and/or mild to moderate bronchial asthma, caused by an IgE-mediated allergy to grass/rye or tree pollen; who are treated with MATA grass or MATA trees as part of their routine medical care

Treatment:

Drug: MATA trees or MATA grass