Ultra Low Dose CT for CACS and AC of SPECT

University of Zurich (UZH)

Status: Completed

Conditions: Coronary Artery Disease

Treatments: Device: Standard dose non-contrast enhanced CT; Device: Ultra low dose non-contrast enhanced CT

Study type: Interventional

Funder types: Other

Identifiers

NCT02458352

USZ-2015-0072

Details and patient eligibility

About

The aim of the study is to compare the CACS obtained from standard dose CT to the CACS obtained from ultra-low-dose scans. Additionally, the usefulness of ultra-low-dose CT for AC of myocardial perfusion SPECT will be assessed.

Enrollment: 105 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients referred for myocardial perfusion SPECT
• Male and Female subjects ≥18 years of age,
• Written informed consent

Exclusion criteria

• Pregnancy or breast-feeding
• CACS of 0 after inclusion of 10 patients with CACS 0
• Stents or implanted cardiac devices (valves, pace makers, ICD)
• Coronary artery bypass grafts

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

105 participants in 1 patient group

Standard dose CT, Ultra-low dose CT

Other group

Description:

Standard dose non-contrast enhanced CT (clinically indicated) and Ultra low dose non-contrast enhanced CT (as part of the trial)

Treatment:

Device: Standard dose non-contrast enhanced CT

Device: Ultra low dose non-contrast enhanced CT