Ultra-Violet Fluorescence Bronchial Cancer Location (UVFBCL)

Centre Hospitalier Universitaire de Saint Etienne

Status: Completed

Conditions: Lung Cancer

Treatments: Procedure: Rigid bronchoscopy with ultraviolet transmission; Other: Biopsy

Study type: Interventional

Funder types: Other

Identifiers

NCT02533518

1008041

2010-A00343-36 (Other Identifier)

Details and patient eligibility

About

Diagnose lung cancer at an early stage is crucial for effective treatment. At these early stages, cancer is usually invisible in ambient white light when the endoscopic analysis of the bronchial mucosa. This lining is self-fluorescent at its illumination by blue light. These widely distributed autofluorescence methods detect early mucosal abnormalities. They are very sensitive but not specific to recognize the lung cancer. Thanks to European funding (EURIMUS), a new tool with fluorescent UV light has been developed.

The purpose of this preliminary study is to verify the suitability for specific detection of cancerous tissue in Pneumology of this fluorescence method versus histological analysis of the tissue.

Enrollment: 30 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient affiliated or entitled to a social security scheme
• Major Patient
• Patient who signed the informed consent document
• Patient with a known primary cancer in bronchial level

Exclusion criteria

• Pregnant woman
• Patient with a benign tumor histology
• Patient with an unknown tumor histology.

Trial design

Primary purpose: Screening

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

30 participants in 1 patient group

patients with lung cancer

Experimental group

Treatment:

Other: Biopsy

Procedure: Rigid bronchoscopy with ultraviolet transmission