Ultrafast Ultrasonographic Oro-laryngeal Measurement in Critically Ill Patients During Weaning From Mechanical Ventilation (REVEAL)

Groupe Hospitalier du Havre

Status: Enrolling

Conditions: Laryngeal Edema

Treatments: Other: Ultrafast ultrasonography

Study type: Observational

Funder types: Other

Identifiers

NCT05611437

2022-A01363-40

Details and patient eligibility

About

In ICU, ventilatory weaning failure is common, accounting for up to 25% of extubations. These failures are largely due to swallowing disorders and laryngeal edema. Edema prevalence in ICU varies between 4 and 37%.

Post-extubation stridor is a clinical sign of upper airway obstruction and may require urgent reintubation, which is associated with increased patient length of stay, morbidity and mortality.

Identifying patients at risk is critical, and the need for reliable tools to predict the occurence of laryngeal edema is still relevant.

Enrollment: 150 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults,
• Intubated and ventilated for more than 24h,
• Filing mechanical ventilation weaning criteria.

Exclusion criteria

• Pregnant of breast-feeding woman,
• Under guardianship patient,
• History of laryngeal tumor, stroke, paralysis of recurrent nerve, swallowing disorders,
• History of surgical laryngeal intervention or radiotherapy,
• Unplanned extubation,
• Opposition to take part in the study.