Ultrasonic Cardiogram Evaluate the Prognosis of Percutaneous Revascularization of Chronic Total Occlusions

Southeast University, China

Status: Unknown

Conditions: Coronary Chronic Total Occlusion

Treatments: Device: stent

Study type: Interventional

Funder types: Other

Identifiers

NCT03300011

2014ZDSYLL120.1

Details and patient eligibility

About

Chronic total occlusions (CTO) are encountered in almost one-fourth of patients undergoing coronary angiography. The presence of an untreated CTO has been related to adverse clinical prognosis, both in stable angina and acute myocardial infarction, and is often associated with persistent symptomatic angina. Depending on their symptomatic and functional status as well as anatomical complexity, CTO can be treated by optimal medical therapy only or therapy combined with coronary revascularization. This study designed to evaluate the safety and efficacy of coronary chronic total occlusion PCI by ultrasonic cardiogram.

Full description

UCEPPCIOCT maintains a prospective clinical registry of all individual who undergo cardiac angiography,PCI or optimistic medicine treatment.

1. research objective to observe the changes of cardiac function postoperative PCI in patients with CTO and the incidence of major adverse cardiovascular events, and provide the reality basis for PCI strategy in clinical patients with CTO . 2. research content: follow up the patients with CTO by using echocardiography in preoperative and postoperative PCI in 1m, 3ms, 6ms, 12ms to assess the changes of cardiac structure and cardiac function. 2, comparison the 'incidence of major adverse cardiovascular events undergo PCI treatment in success and failure group in patients with CTO (such as severe angina attack, severe acute coronary syndrome, severe heart failure should be rehospitalized , fatal arrhythmia and sudden cardiac death, etc.)

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

coronary artery of chronic total occlusion

Exclusion criteria

ACS in 3months; once PCI or CABG; AF

Trial design

Primary purpose: Other

Allocation: Non-Randomized

Interventional model: Sequential Assignment

Masking: Double Blind

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200 participants in 3 patient groups

recanalisation CTO lesion successful

Experimental group

Description:

Patients with CTO lesion performed PCI strategy and successfully recanalisation the CTO lesion with implanted stents .

Treatment:

Device: stent

recanalisation CTO lesion failure

No Intervention group

Description:

Patients with CTO lesion performed PCI strategy and failure recanalisation the CTO lesion with PCI wire and balloon..

OMT

No Intervention group

Description:

Patients with CTO lesion optimal medicine treatment without PCI