Ultrasonographic Evaluation of Diabetic Neuropathy

Ç

Çukurova University

Status

Completed

Conditions

Diabetic Peripheral Neuropathy

Treatments

Other: Ultrasonographic evaluation of nerves in diabetic patients
Other: Ultrasonographic evaluation of nerves of healthy volunteers

Study type

Observational

Funder types

Other

Identifiers

NCT02308059
TF2012BAP13

Details and patient eligibility

About

The current study aimed to evaluate the cross-sectional area (CSA) of peripheral nerves in people with diabetic peripheral neuropathy using ultrasonography and correlate the CSA with clinical and demographic data.

Full description

Patients with diabetic peripheral neuropathy (n=53) and a matched healthy control group (n=53) underwent blinded ultrasonography imaging of the sciatic, tibial and median nerves. Matching was performed according to patient body mass index (BMI), sex and age. CSAs of the nerves were recorded, and the associations between pain intensity (measured with a visual analog scale [VAS]), the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) pain scale, diabetes mellitus duration, BMI, HbA1c and blood glucose levels were evaluated.

Enrollment

106 patients

Sex

All

Ages

18 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

  • type 2 diabetes mellitus
  • Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) scores ≥ 12
  • probable diabetic peripheral neuropathy according to the diabetic peripheral neuropathy criteria.

Exclusion Criteria

  • type 1 diabetes mellitus
  • hypothyroidism
  • LANSS pain scale scores < 12
  • body mass index (BMI) > 35
  • current pregnancy
  • histories of hereditary neuropathy, inflammatory neuropathy, nerve trauma, or other known causes of polyneuropathy; and the use of anti-neuropathic drugs.

Trial design

106 participants in 2 patient groups

Patients with diabetes mellitus
Description:
Group I; the patients with diabetes mellitus who had peripheral neuropathy as diagnosed.
Treatment:
Other: Ultrasonographic evaluation of nerves in diabetic patients
Control
Description:
Group II; healthy volunteers
Treatment:
Other: Ultrasonographic evaluation of nerves of healthy volunteers

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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