Ultrasonography of Optic Nerve Sheath Diameter for Noninvasive Detection of Raised Intracranial Pressure: ORIENT Study

Jilin University

Status: Enrolling

Conditions: Ultrasonography

Treatments: Other: no intervention

Study type: Observational

Funder types: Other

Identifiers

NCT04981548

21K081-001

Details and patient eligibility

About

This study aims to adopt a multi-center large sample size study to define (1) the normal range of Chinese ONSD; (2) ONSD diagnosis for patients with high intracranial pressure; (3) to analyze the correlation between ONSD and intracranial pressure.

Full description

The ONSD, transcranial Doppler parameters and baseline data of the normal intracranial pressure group and the enhanced intracranial pressure group (more than 200 mmH2O) .

Enrollment: 1,000 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. People requiring lumbar puncture testing due to brain trauma, intracranial infection, intracranial vascular disease, intracranial tumors, peripheral neuropathy for the raised intracranial pressure group.
2. Healthy people for the normal intracranial pressure group.

Exclusion criteria

1. eye diseases, such as eye trauma, eye tumors, optic neuritis, and glaucoma
2. People with poor temporal window penetration.
3. Patients who refuse to sign informed consent.

Trial design

1,000 participants in 2 patient groups

raised intracranial pressure

Description:

more than 200 mmH2O

Treatment:

Other: no intervention

the normal intracranial pressure group

Description:

more than 80 mmH2O and no more than 200 mmH2O

Treatment:

Other: no intervention