Ultrasonography SWE for Hepatic Fibrosis Evaluation

Seoul National University

Status: Completed

Conditions: Cirrhosis

Treatments: Device: ultrasound shear wave elastography

Study type: Observational

Funder types: Other

Identifiers

NCT02673411

SNUH-2016-0065

Details and patient eligibility

About

The purpose of this study is to measure diagnostic performance of ultrasound shear wave elastography to detect advanced hepatic fibrosis.

Full description

Hepatic fibrosis causes liver dysfunction and HCC. Since hepatic fibrosis is reversible dynamic condition, its monitoring is important to predict long term outcome and to determine treatment plan.

The reference of standard to diagnose hepatic fibrosis is biopsy, but recently non-invasive method such as stiffness imaging has been drawing a lot of attention. In this study, ultrasound shear wave elastography will be performed and its diagnostic performance to detect advanced hepatic fibrosis (= > F2) will be measured using histologic grade as a reference.

Enrollment: 140 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• volunteers who agree to undergo US shear elastography OR
• patients with chronic liver disease who are scheduled to undergo liver resection or liver parenchymal biopsy.

AND

• = or > 18 years
• sign informed consent

Exclusion criteria

• none