Ultrasound and Endometrial Hyperplasia

Penn State Health

Status: Terminated

Conditions: Endometrial Hyperplasia

Treatments: Procedure: Ultrasound and Biopsy

Study type: Interventional

Funder types: Other

Identifiers

NCT00123188

20175

Details and patient eligibility

About

The investigators hypothesize that endometrial thickness will be a significant predictor of endometrial hyperplasia in a postmenopausal female population with metabolic syndrome: diabetes and/or insulin resistance, hypertension, and obesity.

Full description

The objective is to identify the utility of ultrasound as a screening test for endometrial hyperplasia and cancer in an "at risk" cohort. Endometrial carcinoma is an understudied cancer. This study will provide benefit regardless of its outcome, because it will be the first prospectively designed screening trial in an asymptomatic population.

Enrollment: 36 patients

Sex: Female

Ages: 45 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Postmenopausal obese subjects, who have diabetes or a prediabetic state, or hypertension

Exclusion criteria

• Women who have had a hysterectomy

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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36 participants in 1 patient group

Ultrasound and Biopsy

Experimental group

Description:

Transvaginal Ultrasound and Endometrial Biopsy

Treatment:

Procedure: Ultrasound and Biopsy