Ultrasound and Immunological Findings in Patients With Shoulder Injury Related to Vaccine Administration (SIRVA)

University Hospital Basel

Status: Completed

Conditions: Shoulder Injury Related to Vaccine Administration; Erosion, Localized

Treatments: Diagnostic Test: Ultrasound Shoulder and Immunological Phenotyping by FACS

Study type: Observational

Funder types: Other

Identifiers

NCT04236193

SIRVA

Details and patient eligibility

About

Accidental vaccine injection into adjunct shoulder structures can cause tissue damage, termed Shoulder injury related to vaccine administration (SIRVA). The immunopathological mechanisms and consequences of SIRVA are unknown.

The study assesses the clinical and immunological consequences of an influenza vaccine if accidentally administered in periarticular space.

Enrollment: 30 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• participation at a local vaccination campaign
• Shoulder pain >3 days after vaccination

Exclusion criteria

• no vaccine received
• preexisting shoulder pathology

Trial design

30 participants in 2 patient groups

SIRVA

Description:

Subjects with shoulder pain \>7 days after vaccination

Treatment:

Diagnostic Test: Ultrasound Shoulder and Immunological Phenotyping by FACS

Controls

Description:

Subjects from a prospective influenza vaccine study

Treatment:

Diagnostic Test: Ultrasound Shoulder and Immunological Phenotyping by FACS