Ultrasound Assessment of Atherosclerotic Plaque Burden and Cardiovascular Risk: A 10-Year Prospective Study (P-SONAR)

University Hospital, Akershus

Status: Completed

Conditions: Fatty Liver; Carotid Artery Plaque; Atherosclerosis of Femoral Artery; Atheroscleroses; Stroke; Ischemic Cardiovascular Disease; Cardiovascular Diseases

Study type: Observational

Funder types: Other

Identifiers

NCT06933745

Ahus, BDA

Details and patient eligibility

About

The P-SONAR study is a large, observational, prospective cohort study. The overall aim of the study is to investigate whether plaque burden estimation by 2D ultrasound of the carotid and femoral arteries may enhance cardiovascular risk prediction beyond NORRISK-2

Full description

Design: The P-SONAR Study is a prospective cohort study of all men and women aged 45-74 years attending a health check at one of 10 ultrasound clinics in Norway.

Time schedule: Study inclusion and baseline examinations took place in the period April 2022- March 20025.

Current status: Ultrasound follow-up examinations take place from January 2025 - December 2029.

Enrollment: 21,029 patients

Sex: All

Ages: 45 to 74 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: Persons attending a health check during the study period.

Exclusion Criteria:

• If they do not consent to participate

Trial design

21,029 participants in 2 patient groups

Participants undergoing ultrasound and screening for conventional CV risk factors.

Description:

A sub-cohort consists of 5 500 participants who undergo both carotid and femoral ultrasound and fatty liver status assessment by ultrasound, in addition to assessement of traditional CV risk factors including history of smoking, total-cholesterol, LDL-cholesterol, HDL-cholesterol, Lp(a), blood glucose, systolic and diastolic blood pressure and waist circumference measurements.

Participants undergoing ultrasound examination

Description:

Total cohort consists of 22 000 participants who undergo both carotid and femoral ultrasound and fatty liver status assessment by ultrasound