Ultrasound Based Acoustic Radiation Force Impulse Imaging

University of Michigan

Status: Completed

Conditions: Liver Inflammation; Liver Fibrosis

Treatments: Device: Ultrasound-Based Acoustic Radiation Force Impulse (ARFI)

Study type: Interventional

Funder types: Other

Identifiers

NCT01781208

HUM00063736

Details and patient eligibility

About

ARFI (Ultrasound-based Acoustic Radiation Force Impulse) will be used during ultrasound guided needle biopsy of the liver of children.

Full description

A new technique based on ultrasound, known as Acoustic Radiation Force Impulse (ARFI) imaging is performed using standard approved ultrasound machines and transducers. The sound waves or impulses are generated in a different pattern and offer information on the stiffness of the tissue. This new technique will be evaluated for usefulness in diagnosing different liver conditions.

Enrollment: 62 patients

Sex: All

Ages: Under 18 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18 years of age or younger

• Scheduled to have a needle biopsy of the liver at

  1. C.S. Mott Children's Hospital or
  2. Dept. of Radiology at the Univ. of Michigan Hospital

• Scheduled to have an abdominal ultrasound to evaluate your liver (with no known liver disease)

Exclusion criteria

• None to list

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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62 participants in 1 patient group

Ultrasound-based Acoustic Radiation Force Imaging

Experimental group

Description:

The liver was scanned using ultrasound and ultrasound-based acoustic radiation force impulse imaging technique (ARFI).

Treatment:

Device: Ultrasound-Based Acoustic Radiation Force Impulse (ARFI)