Ultrasound Evaluation of Abdominal Muscle Thickness During Mechanical Ventilation (ABDO-VM)

Centre Hospitalier de Roanne

Status: Completed

Conditions: Ventilation Therapy; Complications

Treatments: Device: Ultrasound

Study type: Interventional

Funder types: Other

Identifiers

NCT04939298

2020/01

2020-A03186-33 (Other Identifier)

Details and patient eligibility

About

Weakness of respiratory muscles is frequent after several days of mechanical ventilation. Thereby an acquired diaphragm weakness has been demonstrated, linked to an atrophy which may be identified by a decrease of muscle thickness in echography. This study aims to evaluate with ultrasound the variation of thickness of abdominal muscles after 7 days of mechanical ventilation.

Full description

Weakness of respiratory muscles is frequent after several days of mechanical ventilation. Thereby an acquired diaphragm weakness has been demonstrated, linked to an atrophy which may be identified by a decrease of muscle thickness in echography. Weakness of expiratory muscles is also frequent after 7 days of mechanical ventilation, however his cause is not clear: is it present at admission notably in elderly patients, or acquired on mechanical ventilation ? Ultrasound allows to measure the thickness of abdominal muscles which correlates with their strength. This study aims to evaluate with ultrasound the variation of thickness of abdominal muscles after 7 days of mechanical ventilation.

Enrollment: 40 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient affiliated or entitled to a social security plan
• Expected duration of mechanical ventilation > 7 days
• Trusted person/relative who has signed a consent to participate in the study

Exclusion criteria

• Patient with a pre-existing neuromuscular pathology
• No access to ultrasound Windows (dressing, drainages...)
• Patient transferred from another intensive care unit
• Patient Under guardianship or curators

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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40 participants in 1 patient group

Patients under mechanical ventilation

Experimental group

Description:

Ultrasound evaluation of the variation of thickness of abdominal muscles after 7 days of mechanical ventilation

Treatment:

Device: Ultrasound