Ultrasound Evaluation of Preventive Measures for Postoperative Lung Atelectasis After Surgery (LUS/PEEP/RM)

Al-Azhar University

Status: Not yet enrolling

Conditions: Pulmonary Atelectasis, Postoperative

Treatments: Other: PEEP/RM; Other: PEEP; Other: PEEP/RM/RF

Study type: Interventional

Funder types: Other

Identifiers

NCT06654778

AZAST/MD/209/MARCH/2024

Details and patient eligibility

About

the aim of this prospective randomized blinded clinical study will be to assess the ultrasound evaluation of different preventive measures of post operative lung atelectasis in abdominal surgeries; these measures include ventilation and fluid measures

Full description

ultrasound evaluation for application of different preventive measures of post operative lung atelectasis, including positive end-expiratory pressure, lung recruitment maneuvers, and restrictive fluid management.

Enrollment: 60 estimated patients

Sex: All

Ages: 30 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA physical status I or II, of either gender.
• BMI < 40
• Age 30-60 years
• scheduled for elective abdominal surgeries

Exclusion criteria

• Patient refusal
• American Society of Anesthesiologists (ASA) physical status classification system more than II
• BMI > 40 .
• Psychiatric disorders
• History of chest disorders such as asthma and obstructive pulmonary disease (COPD).
• History of Previous Thoracic Procedures.
• Pregnancy

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 3 patient groups

Group I: PEEP

Experimental group

Description:

Patients will be ventilated with PEEP of 8 cm H2O and fluid management: 500 ml of Ringer's lactate in the recovery room before surgery and Ringer's lactate at a rate of 4 mL/kg/hour from the beginning to the end of the surgery.

Treatment:

Other: PEEP

Group II: PEEP/RM

Experimental group

Description:

Patients will be ventilated with PEEP of 8 cm H2O, and then RM (30 cm H2O for 30 s) will be applied immediately after the second LUS examination and repeated every 30 minutes till emergence and fluid management: 500 ml of Ringer's lactate in recovery room before surgery and Ringer's lactate at a rate of 4 mL/kg/hour from the beginning to the end of the surgery

Treatment:

Other: PEEP/RM

Group III: PEEP/RM/RF

Experimental group

Description:

Patients will be ventilated with PEEP of 8 cm H2O, and then RM (30 cm H2O for 30 s) will be applied immediately after the second LUS examination and repeated every 30 minutes till emergence and restrictive fluid management (RF). Ringer's lactate at a rate of 3 mL/kg/hour from the beginning to the end of the surgery

Treatment:

Other: PEEP/RM/RF