Ultrasound Findings of Finger, Wrist and Knee Joints in Mucopolysaccharidosis

Children's Hospital of Eastern Ontario

Status: Completed

Conditions: MPS IV; MPS I

Study type: Observational

Funder types: Other

Identifiers

NCT02067650

MPSUS

Details and patient eligibility

About

Hardly any imaging studies specifically addressing the articular and periarticular structures in MPS patients are available at this point. The investigators propose to do for the first time a pilot study using musculoskeletal ultrasound in patients with various types of MPS.

Enrollment: 18 patients

Sex: All

Ages: 2 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria

• Diagnosis of Mucopolysaccharidosis
• Ability to collaborate with the ultrasound assessment
• Written informed consent from parents and patients over 14 years of age, assent from children 7 to 14 years

Exclusion Criteria

• Inability to collaborate with the ultrasound assessment
• Acute trauma to a joint that will be assessed in the 3 months preceding the study
• Coexistence of other pathology that is known to affect the respective joints