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Ultrasound-guided Adductor Canal Block for Total Knee Replacement

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Northwestern University

Status and phase

Completed
Phase 4

Conditions

Knee Injuries
Complications; Arthroplasty

Treatments

Drug: Preservative free normal saline
Drug: Bupivacaine

Study type

Interventional

Funder types

Other

Identifiers

NCT02100579
STU00088239 (Other Identifier)

Details and patient eligibility

About

Total knee arthroplasty is associated with intense early postoperative pain. Fast track recovery programs including early therapy protocols and early hospital discharge are being implemented at various hospitals. The postoperative analgesic pain regimen should enhance functional recovery in addition to providing efficient analgesia with minimal side effects. Adductor canal blockade is commonly used to provide postoperative analgesia for total knee arthroplasty (TKA) surgery. The investigators hypothesize that an ultrasound guided adductor canal block will lower narcotic consumption and improved overall satisfaction compared to ultrasound guided sham block with normal saline (placebo) for patients undergoing minimally invasive TKA surgery.

Full description

The investigators hypothesize that an ultrasound guided adductor canal block will lower narcotic consumption and improved overall satisfaction compared to ultrasound guided sham block with normal saline (placebo) for patients undergoing minimally invasive TKA surgery.

Enrollment

40 patients

Sex

All

Ages

40 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Participants 40 to 75 years old who are presenting for minimally invasive total knee arthroplasty under spinal anesthesia

Exclusion criteria

  • Patient refusal
  • American Society of Anesthesiologists physical status classification of 4 or higher
  • Pre-existing neuropathy in the femoral or sciatic distribution
  • Coagulopathy
  • Infection at the site
  • Chronic opioid use (greater than 3 months)
  • Pregnancy
  • Medical conditions limiting physical therapy participation
  • Any other contra-indication to regional anesthesia

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Triple Blind

40 participants in 2 patient groups, including a placebo group

Active Group
Active Comparator group
Description:
Ultrasound-guided adductor canal blockade with 10 ml of 0.25% bupivacaine
Treatment:
Drug: Bupivacaine
Control Group
Placebo Comparator group
Description:
Ultrasound-guided sham block with 10 ml of preservative free normal saline
Treatment:
Drug: Preservative free normal saline

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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