Ultrasound Guided Autologous Blood Injection in Temporomandibular Joint Dislocation

Cairo University (CU)

Status: Enrolling

Conditions: Temporomandibular Joint Dislocation

Treatments: Procedure: non guided autologous blood injection; Procedure: ultrasound guided autologous blood injection

Study type: Interventional

Funder types: Other

Identifiers

NCT06244134

291123

Details and patient eligibility

About

The aim of this study is To compare the accuracy and effectiveness of ultrasound (US) guided autologous blood injection (ABI) versus non- guided technique for the treatment of chronic recurrent temporomandibular joint dislocation

Full description

All patients involved in this study will be divided randomly to two different groups and injected with autologous blood into joint space and pericapsular tissue.

Study group (group A) will be injected with autologous blood with ultrasound guidance.

control group (group B) will be injected with autologous blood without US guidance. Anatomical landmarks and tactical sense will be followed only.

The operation will be done under local anesthesia ( Auriculotemporal nerve block ) the skin overlying the temporomandibular joint will be scrubbed by an antiseptic solution and the area will be isolated with sterile towels. External auditory canal will be blocked with cotton.

About 3 ml of blood will be withdrawn from patient's antecubital fossa, of which 2 ml injected intra-articular and 1 ml in the pericapsular tissue (PT) The procedure should be repeated on the opposite side in case of bilateral involvement.

Enrollment: 24 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patient with at least 3 episodes of temporomandibular joint dislocation in the past 6 months.
• Necessitating a visit to the emergency room or trained professional to reduce the dislocation.
• Radiological evidence of displacement of condylar head beyond the articular eminence on wide mouth opening.
• Maximum mouth opening (MMO) more than 40 mm.
• Unilateral or bilateral.
• Over 18 years of age.
• Both gender Males or females.

Exclusion criteria

• Patient having inflammatory temporomandibular joint disease like tuberculous arthritis, rheumatoid arthritis.
• Patients with bleeding disorders, pregnancy or bony pathology of temporomandibular joint .
• Allergy to local anesthetic.
• Severe epilepsy or Parkinson's disease.
• Patient on anti-depressants or anti-psychotics.
• Inability to follow-up the patient during the entire follow-up period.
• Patients who had recent fracture at temporomandibular joint level or who had previous surgical interference to temporomandibular joint .
• Refused to sign the written informed consent were also excluded.
• Dystonia

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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24 participants in 2 patient groups, including a placebo group

Study group (group A) will be injected with ultrasound guidance in temporomandibular joint .

Active Comparator group

Description:

uses of ultrasound as a guiding tool for temporomandibular joint injection

Treatment:

Procedure: ultrasound guided autologous blood injection

control group(group B) conventional non guided injection in temporomandibular joint

Placebo Comparator group

Description:

without ultrasound guidance only anatomical landmark will be followed during injection

Treatment:

Procedure: non guided autologous blood injection