Ultrasound Guided Block of Stellate Ganglion Versus Greater Occipital Nerve in Resistant Migraine and Correlation to Calcitonin Gene Related Peptide

Ain Shams University

Status: Enrolling

Conditions: Migraine

Treatments: Procedure: Ultrasound guided Stellate ganglion block; Procedure: ultrasound guided Greater occipital nerve block

Study type: Interventional

Funder types: Other

Identifiers

NCT06662461

FMASU MD14/2024

Details and patient eligibility

About

To investigate the efficacy of Ultrasound guided Stellate Ganglion block in chronic resistant migraine patients in comparison to Greater Occipital Nerve Block correlating its effect to serum CGRP level.

Full description

40 Patients diagnosed with Chronic resistant migraine to 2 anti-migraine drugs for 3 months will be evaluated for inclusion and exclusion. Eligible patients with resistance or intolerability to 2 drugs or more will be classified into two groups by using simple randomization methods through Using a computer-generated random number sequence.

Each group will contain 20 patients one group will undergo ultrasound guided bilateral Greater Occipital nerve Block and the other group will undergo ultrasound guided bilateral Stellate Ganglion Block

Enrollment: 40 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Individuals diagnosed with chronic resistant migraine after using or intolerability to 2 or more of anti-migraine drugs for at least 3 months

Exclusion criteria

• Patients with a space-occupying lesion.
• Coagulation disorders.
• Systemic or local infection and drug allergies.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

Ultrasound guided bilateral Greater Occipital nerve Block

Active Comparator group

Treatment:

Procedure: ultrasound guided Greater occipital nerve block

Ultrasound guided bilateral Stellate Ganglion Block

Active Comparator group

Treatment:

Procedure: Ultrasound guided Stellate ganglion block