Ultrasound Guided Epidural Block in Axial SPA

Sohag University

Status and phase: Completed; Phase 4

Conditions: Epidural Block in Axial Spondyloarthritis

Treatments: Drug: Epidural block with lidocaine and triamcinilone

Study type: Interventional

Funder types: Other

Identifiers

NCT04143165

20/10/2019

Details and patient eligibility

About

Study Design: A randomized, prospective, pilot, controlled trial. Setting: Rheumatology and rehabilitation department Minia University and Sohag University Objectives: To evaluate the effectiveness of caudal epidural injections with triamcinolone and lidocaine in managing limited spine mobility in axial SPA.

Methods: Patients were randomly assigned to one of 2 groups, Group I patients received caudal epidural injections with 1% lidocaine hydrochloride (xylocaine AstraZeneca) 9 mL mixed with 1 mL of triamcinolone 40 milligrams (Kenacort Bristol Myers Squip), whereas Group II patients did not receive. Both groups were age and sex matched and both were under treatment with anti TNF and NSAIDs with or without sDMARDs.

Enrollment: 52 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• all participants fulfilled the ASAS criteria for axial SPA
• all participants under treatment including bDMARDS and sDMARDs beside NSAIDs

Exclusion criteria

• Naive patients not under treatment
• limitation of spine flexion due to non inflammatory causes

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Single Blind

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52 participants in 2 patient groups

Epidural block

Active Comparator group

Description:

Group I patients received caudal epidural injections with 1% lidocaine hydrochloride (xylocaine Astra Zeneca) 9 mL mixed with 1 mL of triamcinolone 40 milligrams (Kenacort Bristol Myers Squip)

Treatment:

Drug: Epidural block with lidocaine and triamcinilone

control group

No Intervention group

Description:

patients did not receive injection