Ultrasound Guided Erector Spinae Plane Block Combined With General Anaesthesia Versus Conventional General Anaesthesia in Lumbar Spine Surgery (US ESP block)

Mohamed Elsayed

Status: Unknown

Conditions: Anaesthetic Drugs, Hypotensive Drugs, Perioperative Analgesia

Treatments: Drug: Multimodal analgesia; Procedure: Erector spinae plane block

Study type: Interventional

Funder types: Other

Identifiers

NCT04302129

operative lumbar spine pain

Details and patient eligibility

About

Ultrasound guided erector spinae plain block combined with general anaesthesia versus conventional general anaesthesia in lumbar spine surgery, it's hypothesized that combined regional anaesthesia with general anaesthesia in lumbar spine surgery may reduce the anaesthetic requirements, aid in controlled hypotension and improve the perioperative pain management.

Full description

Primary outcomes:

• Anaesthetic requirements: based on entropy monitoring(state and response entropy monitoring and the difference as a measure for adequacy of analgesia) and haemodynamic parameters ( heart rate and mean arterial blood pressure) at the following time intervals: before induction, after induction, after giving either ESP block or multimodal analgesia and starting surgical stimulus, at 30 min intervals, at end of anaesthesia, at eye opening.

Secondary outcomes:

• Stress response measurement based on serum cortisol and blood glucose levels
• Controlled hypotensive anaesthesia: various drugs required and doses given
• Intraoperative and postoperative analgesia.
• Postanaesthesia care unit data concerning recovery.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

patients undergoing lumbar spine surgery

Exclusion criteria

• Coagulation disorders.
• BMI > 30 or < 18.5.
• Patients with surgical site infection.
• Patients with unstable spine integrity like fractures or scoliosis.
• Hypertensive ,cardiac and diabetic patients.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

30 participants in 2 patient groups

ultrasound guided erector spinae block and general anaesthesia

Experimental group

Description:

Ultrasound guided erector spine plane block is done after general anaesthesia and prone positioning

Treatment:

Procedure: Erector spinae plane block

Multimodal analgesia with general anaesthesia

Active Comparator group

Description:

Multimodal analgesia given with general anaesthesia in form of ketorolac and paracetamol

Treatment:

Drug: Multimodal analgesia