Ultrasound-guided Erector Spinae Plane Block Versus Retrolaminar Block for Postoperative Analgesia in Thoracotomy

Tanta University

Status: Completed

Conditions: Postoperative Analgesia; Retrolaminar Block; Thoracotomy; Ultrasound-guided Erector Spinae Plane Block

Treatments: Procedure: Ultrasound-guided Erector Spinae Plane Block; Procedure: Control; Procedure: Retrolaminar Block

Study type: Interventional

Funder types: Other

Identifiers

NCT05507281

34580/3/21

Details and patient eligibility

About

Comparing efficacy of Ultrasound-guided Erector Spinae Plane Block versus Retrolaminar Block for Postoperative Analgesia in Patients Undergoing Thoracotomy

Full description

Thoracotomy is one of the most painful surgical procedures. The reported incidence of persistent pain after thoracic surgery (post thoracotomy pain syndrome) has been reported in 20%-70% of patients. Inadequately treated post thoracotomy pain can have several negative consequences. Therefore, pain relief is essential to facilitate coughing and deep breathing and to promote early mobilization.

Thoracic epidural analgesia and thoracic paravertebral block are strongly recommended techniques for managing post thoracotomy pain to reduce opioid use and the related adverse effects as hypoventilation, depression of cough reflex, nausea and vomiting. However, they can be technically challenging to perform and are associated with up to 15% failure rate in Thoracic epidural analgesia and potential risk of pneumothorax in thoracic paravertebral block.

Erector spinae plane block is a relatively novel ultrasound-guided regional technique. Its application in patients with chronic thoracic neuropathic pain and acute surgical pain has been described by Forero et al.

Retrolaminar block is an easy and safe analgesic technique. It has been reported to be satisfactory for post-operative analgesia after breast surgery.

To our knowledge there is no clinical studies, comparing the effectiveness of both blocks on postthoracotomy pain, has been reported.

Enrollment: 60 patients

Sex: All

Ages: 21 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adult patients aged 21-65 years old of both sexes.
• Patients were scheduled for elective thoracotomy.
• Their ASA physical status classification is II-III.

Exclusion criteria

• Patients' refusal.
• Local infection at the site of block.
• Coagulation abnormalities.
• Sever spinal deformity e.g. scoliosis.
• Known hypersensitivity to local anesthetics.
• Mental dysfunction and cognitive disorders.
• History of drug abuse and chronic analgesic use.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 3 patient groups

Control group

Sham Comparator group

Description:

Patients received general anesthesia alone.

Treatment:

Procedure: Control

Ultrasound-guided Erector Spinae Plane Block

Experimental group

Description:

A 22-gauge needle is inserted at a puncture site lateral to the target spinous process using ultrasound imaging and advanced until contact is made with the transverse process. The local anesthetic agent will be injected between the transverse process and the erector spinae muscle using 20 ml (19ml bupivacaine 0.25% plus 1ml dexamethasone 4mg).

Treatment:

Procedure: Ultrasound-guided Erector Spinae Plane Block

Retrolaminar Block

Experimental group

Description:

A 22-gauge needle is inserted at a puncture site lateral to the target spinous process using ultrasound imaging and advanced caudally or cranially until it contacts the lamina. The local anesthetic agent will be injected on the lamina using 20 ml (19ml bupivacaine 0.25% plus 1ml dexamethasone 4mg).

Treatment:

Procedure: Retrolaminar Block