Ultrasound Guided Modified Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA) Versus Quadratus Lumborum Block for Postoperative Analgesia in Laparoscopic Cholecystectomy

Ain Shams University

Status: Enrolling

Conditions: Quadratus Lumborum Block; Laparoscopic Cholecystectomy; Modified Thoracoabdominal Nerve Block

Treatments: Procedure: Modified thoracoabdominal nerve block through perichondrial approach (M-TAPA); Procedure: Quadratus lumborum block

Study type: Interventional

Funder types: Other

Identifiers

NCT06588777

MD92/2024

Details and patient eligibility

About

This study aims to compare the efficacy of using Ultrasound guided modified thoracoabdominal nerve block through perichondrial approach (M-TAPA) versus quadratus lumborum block for postoperative analgesia in laparoscopic cholecystectomy under general anesthesia.

Enrollment: 52 estimated patients

Sex: All

Ages: 21 to 71 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients aging ≥ 21 years to ≤ 70 of both sexes.
• Patients undergoing Laparoscopic cholecystectomy surgeries.
• ASA physical status classes I - II.

Exclusion criteria

• Patient's refusal of procedure or participation in the study.
• ASA classes III or above.
• Coagulopathy and bleeding disorders.
• Evidence of Local skin infections at site of injection.
• Body mass index >40kg/m2
• A history of relevant local anesthetic allergy.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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52 participants in 2 patient groups

Modified thoracoabdominal nerve block through perichondrial approach (M-TAPA)

Experimental group

Description:

Using the in plane technique A deep angle was given to the costochondral angle at the edge of the 10th costal margin with the probe in the sagittal direction to view the lower surface of the costal cartilage in the midline. A 22-G, 100-mm block needle will be inserted in the cranial direction using the in-plane technique and the needle tip will be moved to the posterior aspect of the 10th costal cartilage. It is noted that the needle tip never crossed the cranial edge of the 10th costal cartilage and 20 mL of 0.25% bupivacaine will be injected into the lower surface of the chondrium to make Modified thoracoabdominal nerve block through perichondrial approach (M-TAPA).

Treatment:

Procedure: Modified thoracoabdominal nerve block through perichondrial approach (M-TAPA)

Quadratus lumborum block

Experimental group

Description:

Using the in plane technique the probe will be placed in the mid-axillary line between the lower costal margin and the iliac crest in a transverse plane to view all abdominal layers. The probe will be moved towards the posterior axillary line, to reach a point where all three abdominal muscle layers merge to form aponeurosis. The aponeurosis will then be followed dorsally until the quadratus lumborum muscle is seen deep to transversalis fascia with its attachment to the transverse process of the L4 vertebral body. A 22 G, 100 mm, blunt, insulated nerve block needle will be inserted 1 cm medial to the probe and advanced using the in-plane technique with ultrasound real-time assessment. The injection site will be the junction of transversalis fascia and the anterolateral border of quadratus lumborum muscle.

Treatment:

Procedure: Quadratus lumborum block