Ultrasound-guided Percutaneous Microwave Ablation for Benign Thyroid Nodules

Wenjun Wu

Status: Unknown

Conditions: Thyroid Nodule

Treatments: Device: Microwave Ablation

Study type: Interventional

Funder types: Other

Identifiers

NCT03057925

wwju127

Details and patient eligibility

About

Percutaneous microwave ablation(MWA) was reported as an effective modality for the management of thyroid nodules(TNs). This study aims to validate MWA as a feasible approach for patients with TNs for whom surgery is contraindicated or refused. Two groups of subjects with TNs(one group to treat with MWA and the other group to receive regular ultrasonic follow-up without any treatment) will be evaluated in term of TN volume, ultrasonic image and clinical symptoms.

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age>18 years
• benign thyroid nodules(TYP 2)
• solid or predominantly solid(colloid component<30%)large (>3.0ml) thyroid nodules
• refusal and/or inefficacy of surgery

Exclusion criteria

• pregnancy
• malignant or suspicious thyroid nodules

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

Group A

Experimental group

Description:

MWA Percutaneous Microwave Ablation intervention procedure: Ultrasound-guided Percutaneous Microwave Ablation

Treatment:

Device: Microwave Ablation

Group B

No Intervention group

Description:

untreated no treatment; regular ultrasonic image follow-up