Ultrasound-guided Radiofrequency Ablation of the Genicular Nerve Versus Physical Therapy for Chronic Knee Osteoarthritis

Ankara City Hospital

Status: Enrolling

Conditions: Chronic Knee Osteoarthritis

Treatments: Other: physical therapy; Other: radiofrequency ablation

Study type: Interventional

Funder types: Other

Identifiers

NCT06173830

10026603

Details and patient eligibility

About

The aim of this study is to compare the effects of conventional physiotherapy methods with ultrasound-guided radiofrequency ablation of the genicular nerve on pain and functional status in patients with stage 2-3 chronic knee osteoarthritis.

Full description

Patients diagnosed with Chronic Knee Osteoarthritis according to the American College of Rheumatology criteria, and with radiological osteoarthritis at Kellgren-Lawrence grades 2 and 3, within the age range of 45-70, and meeting the study criteria will be included in the study. After providing information about the procedures to be performed and potential risks to the patients, if they give their written informed consent, treatment methods will be applied to the patients. Eligible patients will be divided into two groups. In one group, Radiofrequency Ablation of the Genicular Nerve under Ultrasound Guidance will be performed, while the other group will receive physical therapy.

Enrollment: 68 estimated patients

Sex: All

Ages: 45 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• VAS ≥ 5
• To be aged between 45 and 70 years old
• Patients diagnosed with chronic knee osteoarthritis using the American College of Rheumatology criteria and having radiological osteoarthritis of Kellgren-Lawrence grade 2 and 3
• Cognitive functions being intact
• Being willing to participate in the study and signing the consent forms

Exclusion criteria

• Having received physical therapy for chronic knee osteoarthritis in the last 6 months
• Having received glucocorticoid or hyaluronic acid injections in the last 6 months
• Having taken oral glucosamine
• Undergoing knee surgery
• Having current neurological or mental disorders
• History of pacemaker usage
• Presence of local infections or sepsis
• Progressive neurological deficit
• Presence of oncological diseases
• Hemorrhagic diathesis or anticoagulation
• Uncontrolled diabetes or other serious internal comorbidities
• Allergy to medications or materials used
• Pregnancy
• Lack of cooperation
• Not willing to participate in the study.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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68 participants in 2 patient groups

Ultrasound-guided radiofrequency ablation of the genicular nerve in chronic knee osteoarthritis

Active Comparator group

Description:

A total of 34 patients with chronic knee osteoarthritis meeting the criteria will undergo ultrasound-guided radiofrequency ablation of the genicular nerve.

Treatment:

Other: radiofrequency ablation

physical therapy for chronic knee osteoarthritis

Active Comparator group

Description:

Thirty-four patients with chronic knee osteoarthritis meeting the criteria will receive 10 sessions of physical therapy.

Treatment:

Other: physical therapy