Ultrasound Guided : Retrolaminar Block Versus Thoracic Epidural Analgesia Following Laparoscopic Cholecystectomy

Zagazig University

Status: Completed

Conditions: Analgesia

Treatments: Procedure: Thoracic epidural analgesia; Procedure: Bilateral retrolaminar block

Study type: Interventional

Funder types: Other

Identifiers

NCT04835415

6777

Details and patient eligibility

About

The aim of this study is to evaluate analgesic effect of ultrasound-guided retrolaminar block vs ultrasound-guided thoracic epidural analgesia in pain control following laparoscopic cholecystectomy.

Full description

To study the difference between the effects of ultrasound-guided bilateral retrolaminar block and ultrasound-guided thoracic epidural analgesia on pain control following laparoscopic cholecystectomy. To relief pain and improve satisfaction in patients undergoing laparoscopic cholecystectomy at Zagazig university hospitals.

Enrollment: 52 patients

Sex: All

Ages: 21 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Written informed consent from the patient.
• Age: 21-45 years old.
• Sex: both sex (males and females).
• Physical status: ASA 1& II.
• BMI = (25-35 kg/m2).
• Type of operation: elective laparoscopic cholecystectomy

Exclusion criteria

• Altered mental state.
• Patients with known history of allergy to study drugs.
• Advanced hepatic, renal, cardiovascular, and respiratory diseases.
• Patients with chronic pain.
• Patients receiving anticoagulants.
• Contraindications of regional anesthesia, e.g., allergy to local anesthetics, coagulopathy, or septic focus at site of injection.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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52 participants in 2 patient groups

group T

Active Comparator group

Description:

Group (T) (n=26): will receive ultrasound guided thoracic epidural analgesia: 20 ml of bupivacaine 0.25 % plus 5ug/ml adrenaline (1:200000).

Treatment:

Procedure: Thoracic epidural analgesia

group R

Active Comparator group

Description:

Group (R) (n=26): will receive bilateral ultrasound guided retrolaminar block analgesia: 20 ml of bupivacaine 0.25 % plus 5ug/ml adrenaline (1:200000).

Treatment:

Procedure: Bilateral retrolaminar block