Ultrasound Guided Serratus Anterior Plane Block Versus Thoracic Erector Spinae Plane Block for Post Operative Analgesia in Pediatrics Undergoing Thoracotomy

Tanta University

Status: Completed

Conditions: Thoracic Erector Spinae Plane Block; Pediatrics; Thoracotomy; Post Operative Analgesia; Serratus Anterior Plane Block; Ultrasound

Treatments: Drug: Control group; Drug: Erector Spinae Plane Block (ESPB) group; Drug: Serratus Anterior Plane Block (SAPB) group

Study type: Interventional

Funder types: Other

Identifiers

NCT06862518

36264MS209/6/23

Details and patient eligibility

About

This study is designed to compare the post operative analgesic effect of serratus anterior plane block versus thoracic erector spinae plane block in pediatrics undergoing thoracotomy

Full description

The incidence of diseases that requires thoracotomy is low in the pediatric age group. Thoracotomy is a severe burden on children and is widely known to cause severe acute pain. This pain can be very distressing for both children and their parents. If not treated properly, it may acutely cause retention of secretion, atelectasis, ventilation-perfusion disorder and hypoxemia, together with a change in lung mechanics.

The serratus anterior plane block (SAPB) has also recently become more popular options for post-thoracotomy analgesia. SAPB involves local anesthetic injection in a plane superficial or deep to the serratus anterior muscle; in both these locations, it blocks the lateral cutaneous branches of intercostal nerves.

The erector spinae plane block (ESPB) is an ultrasound-guided deep plane interfascial block defined by Forero in 2016. It has been shown to provide thoracic and abdominal analgesia. When injected at the T5 transverse process level, the local anesthetic spreads anteriorly through the thoracolumbar fascia and reaches the ventral and dorsal rami of the spinal nerves and posteriorly to the gray and white rami communicantes of the sympathetic chain, providing a C7 to T8 sensitive block. Although it was first described as a chronic pain block, there are increasingly reports about its use in postoperative acute pain.

Enrollment: 105 patients

Sex: All

Ages: 2 to 7 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient aged between 2 and 7 years.
• Patient posted for the right or left thoracotomy under general anesthesia.

Exclusion criteria

• Parents who refuse regional anesthesia.
• Children who had any coagulation abnormality.
• Deformity of the thoracolumbar spine.
• Infection at the site of injection.
• History of allergy to the local anesthetics.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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105 participants in 3 patient groups

Control group

Active Comparator group

Description:

Patients will receive general anesthesia alone

Treatment:

Drug: Control group

Serratus Anterior Plane Block (SAPB) group

Experimental group

Description:

Patients will receive general anesthesia (GA) with ultrasound guided serratus anterior plane block 0.5 ml/kg 0.25% bupivacaine.

Treatment:

Drug: Serratus Anterior Plane Block (SAPB) group

Erector Spinae Plane Block (ESPB) group

Experimental group

Description:

Patients will receive general anesthesia (GA) with ultrasound guided erector spinae plane block 0.5 ml/kg 0.25% bupivacaine.

Treatment:

Drug: Erector Spinae Plane Block (ESPB) group