Ultrasound Guided Steroids Injection Versus PRP for Shoulder Pain Relief

Alexandria University

Status and phase: Completed; Early Phase 1

Conditions: Shoulder Pain

Treatments: Combination Product: Platelet rich plasma; Combination Product: Methylprednisolone

Study type: Interventional

Funder types: Other

Identifiers

NCT05317624

0201491

Details and patient eligibility

About

Comparison between effects of ultrasound guided platelet rich plasma injection versus steroids injection for pain relief in cases of partial rotator cuff tears

Full description

The effect of injection of platelet rich plasma will be compared with effects of steroids injection according to pain relief effects,, Side effects ,, healing ability ,, recurrence in both groups.

30 patient in each group will be included

Enrollment: 60 patients

Sex: All

Ages: 20 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Patients with positive tests for rotator cuff pain
2. Patients with positive radiological (US or MRI) findings of partial rotator cuff tear

Exclusion criteria

1. Patient refusal
2. Age less than 20 years.
3. Infection at injection site.
4. Prior surgery on the shoulder joint area.
5. Presence of other associated pathology in the shoulder joint
6. Patients using antiplatelet drugs (aspirin).
7. Contraindications to the use of platelet concentrate
8. Contraindications to the steroids injection

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 2 patient groups

Platelet rich plasma group

Experimental group

Description:

participants will receive Ultrasound guided subacromial injection of 3 ml platelet rich plasma+0.5 ml of PRP activator (10% calcium gluconate)+ 1ml 0.5%bupivacaine.

Treatment:

Combination Product: Platelet rich plasma

Methylprednisolone group

Experimental group

Description:

participants will receive Ultrasound guided subacromial injection of 1 ml methylprednisolone+ 1ml 0.5%bupivacaine + 2.5 ml normal saline.

Treatment:

Combination Product: Methylprednisolone