Ultrasound-guided Supraclavicular Brachial Plexus Block in Elderly (US-SCB)

Šarić, Jadranka Pavičić, M.D.

Status: Completed

Conditions: Arm Injuries; Anesthesia

Treatments: Device: Elderly population, Middle aged population

Study type: Interventional

Identifiers

NCT01467596

EudraCT 2011-005432-26

Details and patient eligibility

About

The aim of this study is to determine the minimum effective volume of local anesthetic (50:50 mixture of 0.5% levobupivacaine and 2% lidocaine) required to produce an effective US-SCB for surgical anesthesia in 50% of patients and to calculate the effective volume required to produce an effective US-SCB in 95% of the patients (MEAV95) in elderly group (>65 years) and in middle aged group (<45years) of patients.

Full description

We believe that known data regarding the minimum anesthetic volume required for effective US-SCB from middle age population can not be applicable to the elderly population since our preliminary data, presented at Euroanesthesia meeting in Amsterdam, 2011, and published in abstract form in the European Journal of Anaesthesiology, showed that involutional changes of brachial plexus in elderly, assessed by measuring the cross-sectional area (CSA) of brachial plexus at the first rib, allowed a 35% reduction in local anesthetic volume for an effective US-SCB for surgical anesthesia in elderly patients in comparison with the younger patients.

Enrollment: 44 patients

Sex: All

Ages: 18 to 95 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA 1 - 3 elderly patients (>65 years) scheduled for hand surgery
• ASA 1-3 middle aged patients (<45 years)

Exclusion criteria

• Cognitive impairment
• Coagulopathy
• Allergy to local anesthetics
• Infection at the puncture site,
• Body mass index > 35 kg/m2

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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44 participants in 2 patient groups

Elderly population

Experimental group

Description:

MEAV50, MEAV95 Onset and duration of sensory and motor blockade

Treatment:

Device: Elderly population, Middle aged population

Middle aged population

Active Comparator group

Description:

MEAV50, MEAV95 Onset and duration of sensory and motor blockade

Treatment:

Device: Elderly population, Middle aged population