Ultrasound-Guided TAP Block and Spinal Morphine for Pain Relief After Caesarean Section

Sohag University

Status: Completed

Conditions: Post Operative Pain

Treatments: Drug: Morphine; Procedure: Ultrasound-Guided Transversus Abdominis Plane Block

Study type: Interventional

Funder types: Other

Identifiers

NCT05331781

soh-Med-22-2-41

Details and patient eligibility

About

This interventional double-blind randomized controlled study was carried out on 60 cases underwent elective caesarean section delivery, they were divided into 2 groups; patients were randomly allocated into two equal groups; Group M: received intrathecal 150 microgram morphine in a 0.5 ml volume, mixed with 10 mg of hyperbaric bupivacaine 0.5 % in a 2 ml volume (total volume 2.5 ml). Group B: received intrathecal 10 mg hyperbaric bupivacaine 0.5% 2ml volume + 0.5 saline (Total volume 3ml) and at the end of surgery patient received bilateral TAP block with 20 ml volume of 0.25% bupivacaine on each side.

Enrollment: 60 patients

Sex: Female

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• pregnant females scheduled for elective cesarean section

Exclusion criteria

• Patient refusal Patients with known allergies or with past history of allergy to local anesthesia Patients having an infection at the site of injection either in the back or in the abdominal region, Patients with coagulopathy or on systemic anticoagulation, Chronic opioid abuse, significant neurological, psychiatric or neuromuscular disease, Drug abuse and alcoholism, Obesity (BMI 30 and higher), Cardiovascular disease and Endocrine disorders.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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60 participants in 2 patient groups

transversus abdominis plain block group

Experimental group

Description:

post-cesarean section tap block will be given by ultrasound guidance using 20 ml bupivacaine local anesthetic 0.25% concentration for each side as an adjuvant to spinal anesthesia

Treatment:

Procedure: Ultrasound-Guided Transversus Abdominis Plane Block

intrathecal morphia group

Experimental group

Description:

intrathecal 150 microgram morphine in a 0.5 ml volume as an adjuvant to spinal anesthesia

Treatment:

Drug: Morphine