Ultrasound-guided Thermal Ablation for Bethesda III/IV Thyroid Nodules

Chinese PLA General Hospital (301 Hospital)

Status: Enrolling

Conditions: Thyroid Nodule

Treatments: Procedure: ultrasound-guided thermal ablation

Study type: Observational

Funder types: Other

Identifiers

NCT06733753

2024-656

Details and patient eligibility

About

To evaluate the long-term outcomes of ultrasound-guided thermal ablation for Bethesda III/IV thyroid nodules

Full description

To evaluate and predict the long-term clinical outcomes of ultrasound-guided thermal ablation for Bethesda III/IV thyroid nodules

Enrollment: 600 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. confirmation of Bethesda III or IV on fine- needle aspiration and negative on Braf V600E test
2. no clinical or imaging evidences of extrathyroidal extension, lymph node metastasis and distant metastasis on ultrasound, neck and chest CT
3. refusal or ineligibility for surgery
4. follow-up time ≥12 months

Exclusion criteria

1. follicular neoplasm or malignancy findings on biopsy
2. no suspicious of malignancy in US
3. patients with contra-lateral vocal cord paralysis
4. follow- up time less than 12 months

Trial design

600 participants in 1 patient group

ultrasound-guided thermal ablation

Description:

ultrasound-guided thermal ablation

Treatment:

Procedure: ultrasound-guided thermal ablation