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Ultrasound Guided Trigeminal Nerve Block for Typical or Atypical Facial Pain

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Northwestern University

Status and phase

Completed
Phase 4

Conditions

Atypical Facial Pain
Typical Facial Pain

Treatments

Drug: Dexamethasone
Drug: Bupivacaine
Drug: Triamcinolone

Study type

Interventional

Funder types

Other

Identifiers

NCT02024724
STU00083918 (Other Identifier)

Details and patient eligibility

About

Trigeminal neuralgia is a craniofacial pain syndrome that is typically characterized by unilateral severe, recurrent, electrical pain in one or more distributions of the trigeminal nerve. Current treatment strategies include oral medications as first line therapy with surgical interventions reserved for those patients who are refractory to medications or unable to tolerate medication side effects. Despite these current treatment options, many patients continue to have symptoms. Ultrasound-guided trigeminal nerve block allows for fine adjustment of the needle tip and direct observation of the medicine.

Local anesthetic and steroids have been successfully used for diagnostic and or therapeutic nerve pain with great success. Steroids can be short or long acting in duration with varying side effects. If there exists a difference in duration of action, using the longer acting drug will provide a greater period of symptom relief for the patient and may allow the patient to undergo fewer interventional procedures.

Enrollment

60 patients

Sex

All

Ages

18 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • All patients presenting to the Northwestern Pain Center who are eligible and scheduled to receive a ultrasound-guided trigeminal nerve block.

Exclusion criteria

  • Exclusion is the same for patients who are not eligible for ultrasound guided nerve blocks.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Triple Blind

60 participants in 2 patient groups

Dexamethasone
Active Comparator group
Description:
4 mg of Dexamethasone and 4 mL of 0.25% bupivacaine
Treatment:
Drug: Dexamethasone
Drug: Bupivacaine
Triamcinolone
Active Comparator group
Description:
40 mg of Triamcinolone and 4 mL of 0.25% bupivacaine
Treatment:
Drug: Triamcinolone
Drug: Bupivacaine

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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