Ultrasound-Guided Versus Anatomically Guided Botulinum Toxin Injection in Spasticity in Adults in Tanta University Hospitals

Tanta University

Status: Completed

Conditions: Spasticity; Botulinum Toxin; Adults; Ultrasound

Treatments: Drug: Botulinum toxin injection under anatomical landmark; Drug: Ultrasound-guided botulinum toxin injection

Study type: Observational

Funder types: Other

Identifiers

NCT06941883

36264MS248/7/23

Details and patient eligibility

About

This study aimed to compare the safety and outcome of ultrasound (US)- guided botulinum toxin (BoNT) injection and anatomically guided injection in muscle spasticity of different causes in adults.

Full description

One of the major complications of neurological diseases is spasticity which is defined as an increased velocity-dependent muscle tone.

A large volume of clinical data has demonstrated the efficacy and safety of botulinum toxin type A (BoNT-A) products for treating conditions such as spasticity.

Enrollment: 68 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age > 18 years old.
• Both sexes.
• Patients with muscle spasticity.

Exclusion criteria

• Patients with contraindications to botulinum toxin injection as allergy, myasthenia gravis, and cerebral palsy.

Trial design

68 participants in 2 patient groups

Botulinum toxin injection under anatomical landmark

Description:

Patients received botulinum toxin injections under the anatomical landmark.

Treatment:

Drug: Botulinum toxin injection under anatomical landmark

Ultrasound-guided botulinum toxin injection

Description:

Patients received ultrasound-guided botulinum toxin injection

Treatment:

Drug: Ultrasound-guided botulinum toxin injection