Ultrasound in Muscle Biopsy

Duke University

Status: Completed

Conditions: Myositis; Myopathy; Muscular Dystrophy

Treatments: Procedure: Ultrasound

Study type: Interventional

Funder types: Other

Identifiers

NCT01790178

Pro00041999

Details and patient eligibility

About

The objective of the proposed study is to evaluate the clinical utility of muscle ultrasonography for improving the diagnostic yield and safety of core muscle biopsy. Our facility currently uses core (needle) biopsy to obtain muscle samples in patients 18 years old or older. Currently, there is no imaging tool used to guide the actual biopsy. As muscle biopsy is an invasive and potentially painful procedure, improving the diagnostic yield of this test is important.

Enrollment: 40 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Consecutive subjects scheduled for a biopsy at our EMG laboratory will be asked if they would like to participate until a total of 40 participants are obtained.

Exclusion criteria

• Age under 18 years.
• Inability to provide consent for participation.

Trial design

40 participants in 2 patient groups

Ultrasound Guided Biopsy

Experimental group

Description:

Ultrasound guided biopsy will be used in all patients.

Treatment:

Procedure: Ultrasound

Non-Ultrasound Guided Group

No Intervention group

Description:

The control group will have non-ultrasound guided biopsies performed, which is the current standard of care.