Ultrasound of Enthesis in Patients With Ankylosing Spondylitis: a Comparative Study With Health Subjects

University of Sao Paulo

Status: Completed

Conditions: Spondylitis, Ankylosing

Study type: Observational

Funder types: Other

Identifiers

NCT01567878

1649/09

Details and patient eligibility

About

• Evaluate the correlation of ultrasound MASEI index with clinical, functional, radiographic and laboratorial variables in patients with ankylosing spondylitis.
• Evaluate correlation between articular (shoulders, hips, knees and ankles) ultrasound (synovitis, erosions, power doppler) with same variables.
• Evaluate correlation between articular and enthesis ultrasound exam in this study.
• Compare patients and healthy individuals data, to calculate the ROC curve to estimate predictor value of disease.

Enrollment: 80 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Ankylosing spondylitis by the Modified New York Criteria (1984)or ASAS classification (2009)
• Healthy people with no history of joint pain, inflammatory lumbar pain inflammatory disease,
• 18 - 65 years old

Exclusion criteria

• Fibromyalgia
• Corticosteroid injection in the last 3 months
• Previous surgery in joint or enthesis of study
• Peripheric neuropathy
• Diabetes mellitus
• Hypothyroidism
• Peripheric venous insufficiency (with edema or ocre dermatitis)

Trial design

80 participants in 2 patient groups

ankylosing spondylitis

Description:

It will be held ultrasound exam in enthesis and joints in patients with ankylosing spondylitis and healthy subjects

Healthy pelople

Description:

It will be held ultrasound exam in enthesis and joints of healthy subjects