Ultraviolet-A and Riboflavin Treatment for Infectious Keratitis

Cxlusa

Status: Completed

Conditions: Infectious Keratitis

Treatments: Other: Ultraviolet-A and riboflavin

Study type: Interventional

Funder types: Industry

Identifiers

NCT01739673

iCXL

Details and patient eligibility

About

This study is to evaluate the efficacy of ultraviolet-A (UVA) and riboflavin application (also often referred to as corneal collagen crosslinking) as a method to enhance treatment of infectious keratitis.

Enrollment: 13 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Subjects must be 18 years of age or older.
2. Ability to provide written informed consent.
3. Likely to complete all study visits.
4. Subjects must have one eye that with a diagnosis of infectious keratitis.

Exclusion criteria

1. A corneal perforation.
2. Descemetocele.
3. Pregnancy or breastfeeding.
4. Active Herpes corneal disease.
5. Patient is unwilling or unable to comply with a medication regimen and follow up appointments.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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13 participants in 1 patient group

Ultraviolet-A and riboflavin

Experimental group

Treatment:

Other: Ultraviolet-A and riboflavin