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Umbilical Cord-derived Mesenchymal Stem Cell Exosomes on Hair Growth in Patients With Androgenetic Alopecia

N

Nanfang Hospital, Southern Medical University

Status

Active, not recruiting

Conditions

Androgenic Alopecia

Treatments

Drug: Human umbilical cord mesenchymal stem cells

Study type

Interventional

Funder types

Other

Identifiers

NCT06697080
NFEC-2024-323

Details and patient eligibility

About

A total of 50 patients with androgenetic alopecia were selected for the study. Patients who met the inclusion/exclusion criteria were randomly assigned to groups A and B in a 1:1 ratio to receive treatment, with the enrollment date designated as Day 1. Group A visited the clinic once each in the first, second, and third months for treatment with exosomes, while Group B visited the clinic twice each in the first, second, and third months for treatment with exosomes. At the time points of 1, 2, 3, and 6 months after the start of the treatment period, dermatoscopic examinations were conducted on patients in both groups. The differences in hair growth density, hair shaft thickness, and follicle counts within a 1 cm diameter area were compared between the two groups. Additionally, the data differences for each subject at baseline and at the end of the experiment were also assessed.

Enrollment

50 patients

Sex

All

Ages

18 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:Clinical diagnosis of Androgenic alopecia · AGA classification include:The No grade for male hair loss was II-V, and the Ludwig grade for female hair loss was I-III Exclusion Criteria: (1) Using medications or supplements, including finasteride, dutasteride, minoxidil or any other hormonal products, that can affect hair growth; · (2) Patients with severe diseases, immune diseases, endocrine diseases and nervous system diseases; (3) Patients with infection, allergic disease and malignant tumor

Trial design

Primary purpose

Diagnostic

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Triple Blind

50 participants in 2 patient groups

Group A
Experimental group
Description:
Group A visited the clinic once each in the first, second, and third months for treatment with exosomes
Treatment:
Drug: Human umbilical cord mesenchymal stem cells
Group B
Experimental group
Description:
Group B visited the clinic twice each in the first, second, and third months for treatment with exosomes.
Treatment:
Drug: Human umbilical cord mesenchymal stem cells

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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