Unbound Bilirubin Levels in Healthy Term and Late Preterm Infants

Rutgers The State University of New Jersey

Status: Unknown

Conditions: Neonatal Jaundice

Treatments: Other: Assessment of unbound bilirubin levels

Study type: Observational

Funder types: Other

Identifiers

NCT03237715

1

Details and patient eligibility

About

Specific Aim 1: To determine total serum bilirubin (TSB) and unbound bilirubin (Bf) levels in term and late preterm infants during the first week of life.

Specific Aim 2: Measure Bf levels in breast fed and formula fed infants and examine their relationship to unbound fatty acid (FFAu) levels.

Specific Aim 3: To demonstrate that phototherapy results in different changes in TSB and Bf.

Enrollment: 180 estimated patients

Sex: All

Ages: 6 hours to 7 days old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Term and late-preterm infants admitted to the regular care nursery of Robert Wood Johnson University Hospital will be eligible for the study

Exclusion criteria

• Infants suffering from genetic, chromosomal or surgical conditions will be excluded.

Trial design

180 participants in 2 patient groups

Breast fed cohort

Treatment:

Other: Assessment of unbound bilirubin levels

Formula fed cohort

Treatment:

Other: Assessment of unbound bilirubin levels