Underprescribing in Geriatric Patients: a Prevalence Study and Analysis of Factors Contributing to Potential Prescription Omissions (Under-PRES)

Scientific Institute for Research Hospitalization and Healthcare (IRCCS)

Status: Enrolling

Conditions: Older People

Study type: Observational

Funder types: Other

Identifiers

NCT06904638

INRCA_004_2025

Details and patient eligibility

About

This observational study will determine the prevalence of underprescription in a cohort of elderly patients, recruited at the time of an outpatient geriatric visit, or hospitalized, upon admission to a geriatric ward.

Full description

Polypharmacy in older patients is associated with both inappropriate drug prescribing and underprescription or omission of appropriate medications. Potential prescriptive omission (PPO), defined as the underprescription of potentially beneficial drugs, is increasing across all care settings and is associated with adverse clinical outcomes. However, in some cases, PPO may represent a legitimate medical decision.

The aim of this study is to investigate the phenomenon of underprescription by differentiating between justified and inappropriate potential prescriptive omissions (PPOs) in elderly patients in both hospital and outpatient settings, using the Screening Tool to Alert to Right Treatment (START) criteria, version 3.

Enrollment: 374 estimated patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Geriatric ward admission or outpatient geriatric appointment
• Capacity to provide informed consent by the patient or legal guardian

Exclusion criteria

• Limited life expectancy as measured by the Clinical Frailty Scale (CFS) >8

Trial design

374 participants in 1 patient group

older adults

Description:

Geriatric patients admitted to a geriatric hospital unit or attending an outpatient geriatric clinic