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About
The Understanding and Addressing Rejection of Personalized Cancer Risk Information study is a longitudinal observational study conducted to understand the nature of phenomenon of personalized cancer risk rejection in the context of mammography screening.
Full description
The Understanding and Addressing Rejection of Personalized Cancer Risk Information study seeks to understand the nature of the phenomenon of personalized cancer risk rejection in the context of mammography screening by 1) identifying demographic and psychological factors associated with risk rejection and 2) identify how risk rejection influences risk-concordant mammography seeking behavior. The study will test a priori theory-derived hypotheses about the precursors of risk rejection and the influence of rejection on real-life screening decision making.
The Breast Cancer Risk Assessment Tool (BCRAT) will be used to asses participant's breast cancer risk. This model is designed to estimate breast cancer risk in women 35-84, and uses the following predictors: 1) age, 2) age at first menstrual period, 3) age at first live birth, 4) first-degree relatives with breast cancer, 5) previous breast biopsy with atypical hyperplasia, and 6) race/ethnicity Participants will be required to complete the baseline survey in which they receive their Gail model risk estimate and respond to that risk estimate. They will then complete a 12-month follow-up survey.
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Inclusion criteria
Exclusion criteria
Prior diagnosis of
breast cancer
Ductal carcinoma in situ (DCIS)
Lobular carcinoma in situ (LCIS)
Known BRCA1/2 gene mutation
Cowan syndrome
Li-Fraumeni syndrome
Having received previous chest radiation for treatment of Hodgkin's lymphoma.
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Central trial contact
Michelle Eggers; Damilola Jolaoso, MSc
Data sourced from clinicaltrials.gov
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