Understanding Barriers to Initiation and Adherence to Endocrine Therapy in Young Breast Cancer Survivors of Diverse Backgrounds

Dana-Farber Cancer Institute

Status: Completed

Conditions: Breast Cancer

Treatments: Other: Phone interview

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT03447886

U54CA156732 (U.S. NIH Grant/Contract)

17-581

Details and patient eligibility

About

The overall goal of this study is to qualitatively explore how behavioral, cultural, psychosocial, and economic barriers and facilitators affect the decision to start and adhere to endocrine therapy (ET) among young breast cancer survivors of diverse racial, ethnic, and socio-economic backgrounds with hormone receptor positive (HR+) breast cancer

Full description

A qualitative study that will use interviews to gain an in depth understanding of factors affecting the decision to start and adhere to endocrine therapy (ET) among young breast cancer survivors of diverse racial, ethnic, and socio-economic backgrounds with hormone receptor positive (HR+) breast cancer

Enrollment: 17 patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Are Hispanic, Latina, Black, or identify as socio-economically disadvantaged (any racial/ethnic background) as measured by an item of financial distress answering that they are "having difficulty paying the bills no matter what they do" to a question about their current household financial situation.18, 19
• report a history of Stage 1-3 breast cancer
• reports HR+ breast cancer and confirm that they have had a discussion with their doctor about adjuvant ET; OR indicate that they are taking ET, even if they do not know their HR status, answer they are HR-, or do not recall having a discussion about ET)
• not in active treatment (e.g., chemotherapy, radiation), with the exception of Herceptin
• at least 3 months, but no more than 3 years out of completion of active treatment
• no evidence of recurrent/metastatic disease
• at least 18, but< 45 years of age at diagnosis of first invasive breast cancer
• English or Spanish speaking
• are willing to consent to the interview

Exclusion criteria

• HR- breast cancer and indicate they are not taking ET
• HR+ breast cancer but do not confirm discussion of ET or indicate they are taking ET
• Stage 0 (DCIS) breast cancer
• Recurrent or metastatic disease
• Less than 3 months or more than 3 years post-active treatment
• Less than 18 years old or ≥45 years old at diagnosis

Trial design

17 participants in 1 patient group

Quality Of Life

Description:

This study uses qualitative research methods, specifically semi-structured interviews. * This will include moderator guide development, * Phone interviews with breast cancer survivors will be conducted * Qualitative data analysis of the phone interviews will be conducted

Treatment:

Other: Phone interview