Understanding Blood Pressure Changes After Birth

St George's, University of London

Status: Unknown

Conditions: Hypertension in Pregnancy

Study type: Observational

Funder types: Other

Identifiers

NCT05137808

2021.0199

Details and patient eligibility

About

Research Question How does maternal blood pressure respond in the postpartum period for women who had a hypertensive disorder in pregnancy?

Aim To evaluate the recovery of maternal blood pressure after a pregnancy affected by new onset hypertension after twenty weeks gestation

Objectives

• To identify rates of persistent hypertension after pregnancies affected by HDP
• To assess and compare the accuracy of HBPM against the gold standard of ABPM
• To assess the maternal acceptance of HBPM and ABPM
• To explore what CVD-related care information is provided at the 6-8 week GP appointment

Full description

This research aims to investigate how women's blood pressure responds after birth and assess the time it takes to return to normal ranges. This will be calculated by participants undertaking three consecutive days of home blood pressure monitoring, every fortnight from two until twelve weeks postpartum. At twelve weeks postpartum, women will have a twenty-four ambulatory blood pressure assessment. This will highlight the prevalence of persistent high blood pressure and how often GPs will need to monitor women's blood pressure in the immediate few weeks after birth. Women will be asked to complete a questionnaire after their six to eight week GP appointment, assessing if women recall having their blood pressure checked and/or the risks of heart disease explained to them and if they received any lifestyle advice to reduce these risks. Women will be asked to complete a second questionnaire at twelve weeks postpartum assessing their acceptance and preference of home and twenty four hour blood pressure monitoring. This research aims to identify any gaps in the current care of women in the postnatal period and use this information to provide better quality of care to women so they can lead healthier lives and reduce their risk of heart disease.

Enrollment: 300 estimated patients

Sex: Female

Ages: 16+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Pregnant women with a confirmed diagnosis of new onset of high blood pressure after twenty weeks gestation
• Maternal Age >16 years old
• Mental capacity to give informed consent
• Ability to be able to communicate to HCP if their BP range is above target (for example women where English is not their first language).

Exclusion criteria

• Pre-existing hypertension