Understanding Immunity to the Flu Vaccine in COVID-19 Patients

Stanford University

Status

Enrolling

Conditions

Flu Vaccine

Immunity

Corona Virus Infection

Treatments

Biological: Flu shot

Study type

Observational

Funder types

Other

NIH

Identifiers

NCT04579588

5U19AI057229-17 (U.S. NIH Grant/Contract)

IRB-58356

Details and patient eligibility

About

The purpose of this study is to measure immunity to the flu vaccine over time in patients who have had COVID-19 and may have other medical conditions including obesity, type 2 diabetes, chronic fatigue, or long-term COVID-19 symptoms. Adults and children (age 9 to 64) who had been diagnosed with COVID-19 as well as controls without COVID-19 will be invited to participate in this study.

Enrollment

230 estimated patients

Sex

All

Ages

9 to 64 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Age 9 through 64 years
Diagnosed with COVID-19 at least 2 months prior enrollment
Patients with or without obesity, diabetes, chronic fatigue and/or long term COVID-19 symptoms
Patients without COVID-19 diagnosis for controls

Exclusion criteria

Received the influenza vaccine less than 4 months ago
Pregnant or lactating
Patients with special risks attendant to venipuncture
Use of immunomodulatory medications that may impact vaccine immune response per clinician's judgment
Contraindication to the flu vaccine
Immunodeficiency or autoimmune disease that may impact vaccine immune responses per clinician's judgement