Understanding Ketamine's Dissociative Effects (KD Study)

Stanford University

Status and phase: Enrolling; Phase 1

Conditions: Epilepsy

Treatments: Drug: Ketamine

Study type: Interventional

Funder types: Other

Identifiers

NCT04861051

60085

Details and patient eligibility

About

The purpose of this study is to understand how ketamine brings about dissociative symptoms.

Full description

The goal of this proposed research is to record the effects of ketamine on brain activity to understand the changes that occur during dissociation in epilepsy patients with stereoEEG.

Enrollment: 20 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient in Stanford Epilepsy Monitoring Unit
• Age >18 years old.

Exclusion criteria

• Lifetime psychotic or bipolar disorder
• Inability to speak, read or understand English
• Pregnant or nursing females
• Prior adverse ketamine response

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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20 participants in 1 patient group

Ketamine

Other group

Description:

Study participants will receive 0.5mg/kg of ketamine - one single infusion

Treatment:

Drug: Ketamine